Italian Genome Databases
"With the ever-increasing use of genomic data, I am confident that many more such fruitful interactions between molecular and population genetics will take place. A take-home message is that more needs to be done to integrate training in population, molecular, and computational approaches to provide the next generation of researchers with the broad range of knowledge they will need".
Brian Charlesworth
Charlesworth B. What Use Is Population Genetics? Genetics. 2015 Jul;200(3):667-9 link

The central area of interest of the laboratory is the application of the principles of population genetics to data coming from emerging genotyping and sequencing technologies. Much of our work investigates the genetic variability of the Italian population
Our primary goal is to map the genetic variation within the Italian population, in individuals with (geographic) ancestry from the Italy at least from three generations. The secondary goal of the project is to look for links between these genetic variants and phenotypes, and to understand their relevance for health and disease. The information gathered until now on the frequencies of many single nucleotide polymorphisms (SNPs) have allowed us to describe the structure and origins of the Italian population and optimize the design of case-control studies .

On-going research projects:

1. ITALIAN GENOME PROJECT (IGP)
2. ITALIAN GENOME-WIDE DATABASE (IGDB)
3. (NEW!) ITALIAN GENOME BIODIVERSITY PROJECT (IGBP)