ISTITUTO ITALIANO PER LA MEDICINA GENOMICA

Ricerca e Innovazione sul Territorio
OPEN POSITION 1 NEW!!
Early-stage researcher with cell culture and biochemistry background
The Statistical Inference and Biological Modeling lab is seeking a highly motivated early-stage researcher with a strong background in mammalian cell culture, metabolic gene modification, cancer metabolism, and large-scale metabolic modeling interested in gaining experience in a growing multidisciplinary and dynamic research environment.
See "Bandi e offerte di lavoro" for details.
OPEN POSITION
Post-doc position in "Genetically-encoded fluorogenic biosensor for drug discovery"
The Chemical Biology unit is seeking for a highly motivated post-doc to develop novel biosensor technology for drug development and biomarker discovery. The ideal candidate should have a degree in Biotechnology, Bioengineering, Biochemist, or a related field. The position is available immediately and applicants will be considered until the vacancy is filled. See "Bandi e offerte di lavoro" for details.
IN THE SPOTLIGHT
Memory CD8+ T cell, B cell responses, and SARS-CoV-2 protection after mRNA vaccination
Current SARS-CoV-2 vaccine recipients differ in infection history and the magnitude of their elicited antibody response.
A large human cohort distinguished by these parameters are queried for effector memory T cell subsets, memory B cells and ability to recognize epitopes from SARS-CoV-2 variants of concern.
IN THE SPOTLIGHT
FOXA1 regulates alternative splicing in prostate cancer

Lo studio ha identificato un nuovo ruolo per il noto oncogene del tumore alla prostata FOXA1, dimostrandone la funzione chiave nel controllo dello "splicing" alternativo, e quindi nell'influenzare la nascita di varianti geniche nel cancro. L'identificazione di tali varianti può aiutare a predire la prognosi della malattia e le varianti stesse possono rappresentare nuovi bersagli farmacologici per migliorare la sopravvivenza dei pazienti. Cell Rep. 2022