Trapezio – Paving the way to research excellence and talent attraction

La Fondazione Compagnia di San Paolo ha lanciato un bando dal titolo TRAPEZIO – Paving the way to research excellence and talent attraction (consultabile qui)

L'Italian Institute for Genomic Medicine (IIGM) è un ente eleggibile a ricevere proposte come Host Institution per progetti in risposta al Target 2 di TRAPEZIO: MSCA Seal of Excellence - European H2020 Individual Fellowships and Horizon Europe Postdoctoral Fellowships.

Questo target è destinato a finanziare i ricercatori che hanno ottenuto il Seal of Excellence (SoE) in risposta ad un bando della Commissione Europea "Marie Sklodowska-Curie Actions - Horizon 2020 European Individual Fellowships e Horizon Europe Postdoctoral Fellowships". La Commissione europea assegna il SoE a tutte le proposte che hanno ottenuto un punteggio pari o superiore all'85% nell'ambito del bando, ma che non sono state finanziate a causa di limiti al budget disponibile. La Fondazione Compagnia di San Paolo intende, quindi, offrire ai titolari di SoE l'opportunità di condurre il proprio progetto di ricerca presso una Host Institution presente sul territorio del Piemonte o della Liguria.

Le condizioni e i requisiti per presentare una domanda per questo bando che preveda IIGM come istituzione ospitante sono disponibili qui.

The Statistical Inference and Biological Modeling lab @IIGM, headed by Andrea Pagnani, is seeking a highly motivated early-stage researcher with a strong background in mathematics/physics. The host institution Italian Institute for Genomic Medicine (IIGM, is located at the FPO IRCCS Candiolo Cancer Institute, (Turin), Italy ( The main goal of IIGM is to foster and develop excellence in translational medicine, immunology, genomic research, and education, with a strong focus on cancer. The institute provides high-level scientific education and access to state-of-the-art research facilities.

The core activity of the Statistical Inference and Computational Biology unit is the development of statistical mechanics-inspired computational techniques for the analysis of experimental datasets and in particular for inference problems in complex biological systems.

Research: We encourage applications from talented scientists, who are interested in gaining experience in a growing multidisciplinary and dynamic research environment that integrates expertise in hard sciences such as Physics and Mathematics, computational biology in the context of large-scale inference from biological sequence data.
Position: The candidate will learn how to combine a variety of advanced statistical methods tools specifically tailored to the problem of analyzing large datasets of homologous sequence data, and sequences emerging from mutational scanning experiments.

Qualifications and requirements:
? Ph.D. degree in Mathematics, Physics or related fields;
? Strong programming skills (Python, Julia, C, C++);
? Experience in multivariate statistics and inference;
? Good communication skills and self-motivation;
? Fluent in spoken and written English

Mandatory requirements:
To apply for this position please submit (e-mail to:
1. A cover letter (in English) describing research experiences, interests, motivation
2. An updated Curriculum Vitae.

Offered contract: One-year fellowship.
Offered positions: no. 01 - available immediately, the call will remain open until the position is filled.

The Italian Institute for Genomic Medicine (IIGM) is a research institute located at FPO-IRCCS Candiolo Cancer Institute, Candiolo, Turin, Italy ( The main goal of IIGM is to foster and develop excellence in human genomic research and education, with special reference to genomics, epigenomics, and immunology,, with a strong focus on cancer. The institute provides high-level scientific education, and access to state-of-the-art research facilities.

We are currently seeking a technical assistant to work in the field of applied tumor immunology. In our group we generate tumor-targeting monoclonal antibodies (mAbs) and develop them for therapeutic purposes. We use the targeting information of these novel mAbs to develop chimeric antigen receptors (CARs) for the generation of CAR T cells (or CAR NK cells) and/or the generation of bispecific T cell engagers (BiTEs). All these steps will be performed using recombinant antibody technology. This is a full time position.

In this role, you will:
? Generate and screen hybridoma libraries raised against solid tumors (especially colorectal cancer and osteosarcoma).
? Validate the specificity of the targeting by immunohistochemistry approaches on tumor and healthy tissues.
? Culture and characterization of human-derived primary CRC and osteosarcoma cultures.
? Perform translational studies to evaluate gene expression profile for potential antigens in tumor patient samples.
? Work in a team environment with basic biologists, bioinformatics and clinicians.

? Degree in the field of molecular or cellular biology, in biotechnology, ?technico di laboratorio biomedico', or at least 3 years of experience as technician in molecular biology laboratories
? Practical background in molecular, cell biology and/or biochemistry
? Excellent interpersonal and communication skills with basic skills in English
? Research experience with animal work (surgical skills) would be an advantage
? Ability to work independent (following detailed protocols)
? Strong organizational skills

Please send your application, letter of recommendation (if available) and curriculum vitae to:
Prof. Tobias Haas