The Candiolo Genomics Centre is a partnership between the Genomics Units of Istituto Nazionale Oncologico Candiolo (iNOC) and Italian Institute for Genomics Medicine (IIGM). The Centre’s core mission is to provide state-of-the-art sequencing and bioinformatics services for the research groups of iNOC and IIGM as well as to support the iNOC’s Biobank and large-scale clinical sequencing projects. The Centre also offers its sequencing and bioinformatics services to external users from academia and industry. An additional important mission of the Centre is to drive innovation by implementing customized workflows, with a focus on their application to challenging clinical specimens, such as FFPE tissues.
Type of services offered
- Standard sequencing services, including whole-exome (WES), whole-genome (WGS) and RNA sequencing on Illumina platforms.
- Specialized sequencing services, including Nanopore WGS and direct RNA sequencing; 10x Genomics single-cell and spatial assays; and metagenomics.
- Bioinformatics services, including demultiplexing and QC, end-to-end bioinformatic support for clinical projects, and support for sequencing data storage and archiving on public repositories.
Main technologies/platforms available
- Illumina platforms (NovaSeq 6000; NextSeq 500; MiSeq)
- Nanopore platforms (PromethION 24; GridION)
- 10x platforms (Chromium X; CytAssist)
- Robotics for high throughput and miniaturization (Biomek i7; Tecan Freedom EVO; Hamilton; I.DOT)
- Vizgen MERSCOPE for highly multiplexed DNA/RNA fluorescence in situ hybridization (FISH)
Type of samples accepted
- Extracted nucleic acids from any species, including microbial DNA for metagenomics
- Immortalized cell lines (human and mouse)
- PBMCs and organoids
- Fresh-frozen and FFPE tissues (human and mouse)